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I think we are tilting on two different axis. The only way I can see more strain on the wrist if you tilted the headstock lower to the floor. I can see that would be problematic. I am talking about the flat plain of the guitar. Keep the head stock elevated to a comfortable position then tilt the guitar so that the sound hole is no longer pointing out perpendicularly but so that it is actually pointing down a little. The top of the guitar body tilts away from your body while the bottom remains in place. You will feel contact with the front edge of the guitar corner resting on you leg, the trailing edge (the one closest to the body does not touch your leg.) The extreme 90 degree shift would put the guitar face down with the strings in you lap and you woud be looking at the flat back. In this position you need zero wrist flexion! You would not hear anything obviously due to the muted strings. Some where in between the two you might find the place that you feel good about how the wrist is flexing.